CytogeneticsSeqWright's CLIA certified, GLP compliant Affymetrix-based cytogenetics services enable the detection of a broad range of chromosome aberrations affecting phenotypes*. The high-resolution array utilized in our service detects 2.7 million markers across the entire genome, including 400,000 SNPs to detect small structural changes and regions of autozygosity. Unbiased, whole-genome coverage at the highest resolution SeqWright's Cytogenetics services utilize the Affymetrix® Cytogenetics Whole-Genome 2.7M Array which provides the greatest power to detect known and novel aberrations across the entire genome. With unbiased, whole-genome coverage and the highest density of 2.7 million copy number markers, this array enables us to detect even the smallest submicroscopic aberrations, including those that would have been missed with classical techniques. Our Cytogenetics services provide dense coverage of the RefSeq genes, cancer genes, miRNA regions, and haploinsufficiency genes. In addition, the Whole-Genome 2.7M Array includes 400,000 single nucleotide polymorphisms (SNPs) that enable us to detect loss of heterozygosity (LOH), uniparental disomies (UPD), and regions of the genome that are identical-by-descent. Benefits:
Sample Requirements We require as little as 100ng of genomic DNA and accept a variety of sample types commonly used in cytogenetics research including, amniotic fluid, blood, cell lines, chorionic villi (CVS), fresh frozen tissue, and cell lines. *This test is currently for research use only. It has not been approved for diagnostic use by the FDA. |
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